Frequently Asked Questions
Pharmacy
Q: We have in stock sterile 10 ml syringes of sterile saline. Is it necessary for the site pharmacist to prepare syringes of 3 ml saline flush? A: We have requested that the flushes be drawn up to alleviate the risk of administering too much flush. From a patient safety aspect we strive to prepare individual doses for patients and not rely on ther healthcare practitioners to measure out or manipulate the drug particularly for IV preperations.
Enrollment
Q: We have an elligible patient, but I won't be taking them to the OR for procedure until tomorrow morning. Should I randomize the patient now, or wait until tomorrow just before I plan to go to the OR? (assuming the subject is randomized to surgery + t-PA)
A: The operative procedure should occur as close as possible to the time of randomization for those subjects randomized to surgery (MIS plus rt-PA or endoscopy). If the surgical procedure is postponed to accommodate scheduling (i.e., it is preferable to wait until 6 am instead of midnight), a CT scan should be repeated to confirm stability of the ICH and blood pressure stability should be confirmed prior to beginning the surgical procedure. The first dose of study drug should be administered three or more hours after the surgical procedure for those subjects randomized to the MIS plus rt-PA procedure.
Dosing
Data Collection
Follow Up
Miscellaneous